What is the NeuronUP randomized clinical trial about?

A randomized clinical trial testing a cognitive rehabilitation and quality-of-life program using the NeuronUP cognitive stimulation platform combined with occupational therapy for older adults with Alzheimer's disease.

What were the main objectives of the study involving NeuronUP?

To evaluate whether combining occupational therapy with NeuronUP can improve or maintain cognitive status, increase treatment adherence, and enhance quality of life in older adults.

How was the randomized clinical trial designed?

A randomized controlled design with 20 participants split into an experimental group (occupational therapy plus NeuronUP) and a control group (occupational therapy only), with assignment via the Oxmar program.

Who were the study participants and what were the inclusion criteria?

Twenty permanent residents over 60 diagnosed with Alzheimer's disease, without comorbid conditions, possessing adequate manual dexterity to use devices and regularly attending occupational therapy.

What role did NeuronUP play in the research?

NeuronUP provided the cognitive stimulation platform and specialized materials, contributed funding, and offered ongoing communication support to facilitate implementation and dissemination of the study.

Where can the full NeuronUP study be accessed?

The full article is available through MDPI at https://www.mdpi.com/2077-0383/13/19/5982.

Clinical trial: Cognitive stimulation with NeuronUP in people with Alzheimer’s disease

In this article, researcher Anthia Cristina Fabara Rodríguez presents the study “Cognitive rehabilitation and quality of life program through NeuronUP in older adults with Alzheimer’s disease: a randomized clinical trial”, in which our neurorehabilitation platform, NeuronUP, participated.

Relevance of the study

This study focuses on:

Evaluate whether the combination of occupational therapy with the NeuronUP cognitive stimulation platform can improve or maintain the cognitive status of individuals without cognitive impairment or with mild impairment.
It also seeks to determine whether the use of NeuronUP contributes to greater treatment adherence and to the improvement of users’ quality of life.

The importance of this research lies in the possibility of identifying digital tools that optimize cognitive health outcomes, supporting personalized and effective therapies for the early prevention of cognitive decline.

Study methodology

The study methodology included 20 people over 60 years of age, permanent residents in a facility, diagnosed with Alzheimer’s disease and without comorbid conditions. All participants had adequate manual dexterity to use the device and regularly attended occupational therapy sessions.

Participants were randomly divided into an experimental group (10 people) and a control group (10 people) using the Oxmar program for assignment. The experimental group received conventional occupational therapy combined with the NeuronUP cognitive stimulation program, while the control group only participated in conventional occupational therapy. This allowed evaluation of whether the use of NeuronUP, together with occupational therapy, helped to improve or maintain the participants’ cognitive abilities.

Contribution of NeuronUP

NeuronUP provided the necessary resource platform to develop this program, offering access to its cognitive stimulation tools and specialized materials that were integrated into the study. Additionally, NeuronUP contributed to the funding of the article, supporting the research team in carrying out and disseminating their findings. It also provided ongoing communication and addressed questions during the project’s development, which facilitated effective collaboration.

Direct access to the study

People interested in learning the details of the study can access it here.