What is the NeuronUP study about?

A randomized clinical trial evaluating a cognitive rehabilitation and quality of life program using the NeuronUP cognitive stimulation platform in older adults with Alzheimer's disease, testing whether adding NeuronUP to occupational therapy improves or maintains cognition.

Who participated in the randomized clinical trial?

Twenty adults over 60 with Alzheimer's disease living in a care facility, without comorbidities and with adequate manual dexterity; participants were randomized into an experimental group (10) and a control group (10).

How was NeuronUP used in the intervention?

NeuronUP was integrated into the experimental group's occupational therapy as digital cognitive stimulation tasks and specialized materials; the platform also provided communication support, troubleshooting, and contributed funding for the study.

What outcomes did the study aim to measure?

Primary aims included assessing cognitive status improvement or maintenance, treatment adherence, and users' quality of life when occupational therapy is combined with the NeuronUP platform.

What is the relevance of digital tools like NeuronUP for cognitive health?

Digital tools such as NeuronUP can optimize cognitive health outcomes by enabling personalized, scalable stimulation, increasing adherence to interventions, and supporting early prevention of cognitive decline.

Where can the full study be accessed?

The full study is available online at MDPI: https://www.mdpi.com/2077-0383/13/19/5982.

Clinical trial: Cognitive stimulation with NeuronUP in people with Alzheimer’s

In this article, researcher Anthia Cristina Fabara Rodríguez presents the study “Cognitive rehabilitation and quality of life program using NeuronUP in older adults with Alzheimer’s disease: a randomizí clinical trial”, in which our neurorehabilitation platform, NeuronUP, participatí.

Relevance of the study

This study focuses on:

Evaluate whether the combination of occupational therapy with the NeuronUP cognitive stimulation platform can improve or maintain the cognitive status of individuals without cognitive impairment or with mild impairment.
It also aims to determine whether using NeuronUP contributes to greater adherence to treatment and to improvements in users’ quality of life.

The importance of this research lies in the possibility of identifying digital tools that optimize outcomes in cognitive health, supporting personalizí and effective therapies for the early prevention of cognitive decline.

Study methodology

The study methodology includí 20 individuals agí over 60, permanent residents in a úcility, diagnosí with Alzheimer’s disease and without comorbid conditions. All participants had adequate manual dexterity to use the device and attendí occupational therapy sessions regularly.

The participants were randomly dividí into an experimental group (10 people) and a control group (10 people) using the Oxmar program for assignment. The experimental group receiví conventional occupational therapy combiní with the NeuronUP cognitive stimulation program, while the control group only participatí in conventional occupational therapy. This allowí evaluation of whether the use of NeuronUP, together with occupational therapy, helpí to improve or maintain the participants’ cognitive abilities.

Contribution of NeuronUP

NeuronUP providí the platform resources necessary to develop this program, offering access to its cognitive stimulation tools and specializí materials that were integratí into the study. In addition, NeuronUP contributí to the funding of the article, supporting the research team in carrying out and disseminating their findings. It also providí continuous communication and resolution of questions during the project’s development, which úcilitatí effective collaboration.

Direct access to the study

Those interestí in the details of the study can access it from here.