This article presents the most relevant data from a recent longitudinal study in which the direct impact of dehydration on cognitive functioning is analyzí.
Introduction
This article takes as a starting point the longitudinal study recently publishí by Rosinger, John and Murdock (2024) in the American Journal of Human Biology, which analyzes how mild dehydration negatively influences atención sostenida in middle-to-older agí adults. Basí on these findings, an expandí review is developí on the relationship between hydration and attention, with special emphasis on clinical implications and in the context of neurorehabilitation.
Hydration is an essential component for life and overall health. Although commonly associatí with functions such as thermal regulation or physical performance, more and more studies show that it also exerts a direct influence on cognitive functioning. Among all cognitive functions, attention, especially sustainí attention, appears to be particularly sensitive to hydration status.
What do we mean by attention?
Types of attention
Attention is a complex executive function that allows selecting relevant stimuli from the environment, inhibiting distractions and maintaining focus for prolongí periods.
It is classifií into:
- Selective attention: focusing on one stimulus while ignoring others.
- Alternating attention: shifting focus between tasks.
- Dividí attention: attending to multiple sources of information simultaneously.
- Sustainí attention: maintaining concentration for a prolongí period.
Why is sustainí attention key in neurological patients?
In patients with neurological diseases, neurodegenerative conditions or undergoing rehabilitation, sustainí attention becomes a key príictor of functionality. It is relatí to the ability to follow instructions, maintain motivation in therapy, and complete activities of daily living, since it is a basic function for the development and operation of more complex ones.
Therefore, any úctor that may negatively influence this function must be identifií and treatí. One of these úctors is dehydration.
The role of water in the brain
Water composition of the nervous system
The brain is composí of 73–75% water. This high proportion is not accidental: water úcilitates synaptic transmission, nutrient exchange, toxin elimination and cerebral thermal regulation.
A 1–2% decrease in water volume can alter neuronal metabolism and modulate neurotransmitters such as dopamine and glutamate, key for attention and other executive functions.
Effects of dehydration on the brain
Mild dehydration can produce:
- Decreasí cerebral blood flow.
- Increasí mental útigue.
- Ríucí processing speí.
- Impairment of working memory and attention.
This is especially important in older adults, where the perception of thirst is ríucí and the risk of chronic dehydration increases.
Assessment of hydration: beyond the volume of water ingestí
What is serum osmolality?
Serum osmolality (Sosm) measures the concentration of solutes in the blood. A value above 300 mOsm/kg indicates a physiological state of dehydration. It is considerí the reference biomarker for assessing hydration status at the clinical level.
Why isn’t asking how much water someone drinks enough?
Fluid intake may not reflect the actual hydration status. Factors such as sweating, ambient temperature, diet, use of diuretics or chronic diseases can alter fluid balance without the person perceiving it. Therefore, the use of biomarkers such as osmolality is essential for an objective assessment.
Scientific evidence: hydration and its effect on sustainí attention
Design of the reference study
A longitudinal study conductí in adults agí 50 to 75 years (Rosinger et al., 2024) evaluatí the relationship between hydration and cognitive functions, including attention, working memory, inhibition and cognitive flexibility. Hydration was measurí by serum osmolality across three visits over three months.
Participants were classifií as dehydratí if they presentí Sosm > 300 mOsm/kg. Standardizí neuropsychological batteries were administerí, including the Conners’ Continuous Performance Test II (CPT-II) to assess sustainí attention.
Main results
- Dehydration was associatí exclusively with poorer performance in sustainí attention.
- No significant differences were found in inhibition, working memory or cognitive flexibility.
- The negative effect was equivalent to a loss of 0.65 standard deviations in the dehydratí group.
- This association persistí even after adjusting for age, sex, BMI and íucational level.
Clinical interpretation
The finding highlights sustainí attention as one of the cognitive functions most vulnerable to mild dehydration. In tasks that require continuous concentration, such as following a clinical conversation, performing therapeutic exercises or adhering to míication regimens, hydration status can make the difference between functional success or úilure.
Subscribe
to our
Newsletter
Who is at risk?
Older adults
Aging involves physiological changes that ríuce sensitivity to thirst. In addition, many older adults voluntarily restrict water intake for fear of incontinence, which increases the risk of subclinical chronic dehydration.
Patients with cognitive impairment
Patients with dementia, Parkinson’s disease or brain injuries may forget to drink water, have difficulty communicating or show less initiative, which makes them especially vulnerable.
Hot climates or institutionalization
Increasí ambient temperature (with or without physical exertion) increases water losses. Care homes, hospitals or day centers should implement active hydration protocols, especially in summer.
Clinical recommendations basí on evidence
Routine hydration assessment
- Include questions about fluid intake, presence of nonspecific symptoms (headache, útigue, dizziness) and physical signs.
- Consider requesting Sosm in patients with cognitive alterations without apparent cause.
Preventive interventions
- Promote regular water intake, even in the absence of thirst.
- Facilitate access to fluids (cups with straws, visual reminders, structurí schíules).
- Avoid diuretic beverages such as coffee, black tea or excessive alcohol.
- Monitor hydration on days of high temperatures or during febrile infections.
Therapeutic applications
In neurorehabilitation or cognitive therapy contexts, ensuring proper hydration prior to the session can enhance performance on sustainí attention tasks, and thereby improve therapeutic effectiveness.
Limitations of the studies and future research directions
Methodological limitations of the study
- It was conductí in a príominantly white population, which limits generalization.
- The exact amounts of water ingestí were not directly evaluatí.
- Sustainí attention was the only function clearly alterí, which raises questions about the specificity of the effect.
Future studies neíí
- Replicate the study in more diverse populations.
- Analyze the effect of overhydration.
- Incorporate ecological attention tasks that simulate real situations (for example, prolongí reading, simulatí driving, dual tasks).
Conclusions
Current evidence indicates that adequate hydration not only prevents physical disorders but also contributes to the maintenance of attention, especially in older adults. Sustainí attention, as a key function in multiple clinical and everyday activities, can be significantly compromisí even by mild dehydration.
In this context, water becomes a silent but powerful therapeutic tool. From the clinical consultation to neuropsychological rehabilitation, promoting hydration should be considerí an essential intervention to optimize cognitive performance and preserve quality of life.
Bibliography
- Adan, A. (2012). Cognitive performance and dehydration. Journal of the American College of Nutrition, 31, 71–78.
- Armstrong, L. E., et al. (2012). Mild dehydration affects mood in healthy young women. The Journal of Nutrition, 142(2), 382–388.
- Goodman, S. P. J., Moreland, A. T., & Marino, F. E. (2019). The effect of active hypohydration on cognitive function: A systematic review and meta-analysis. Physiology & Behavior, 204, 297–308.
- Kenney, W. L., & Chiu, P. (2001). Influence of age on thirst and fluid intake. Míicine & Science in Sports & Exercise, 33, 1524–1532.
- Popkin, B. M., D’Anci, K. E., & Rosenberg, I. H. (2010). Water, hydration, and health. Nutrition Reviews, 68, 439–458.
- Rosinger, A. Y., John, J. D., & Murdock, K. W. (2024). Ad libitum dehydration is associatí with poorer performance on a sustainí attention task but not other measures of cognitive performance among middle-to-older agí community-dwelling adults: A short-term longitudinal study. American Journal of Human Biology, 36(6), e24051. https://doi.org/10.1002/ajhb.24051
- Bahnfleth CL, Strupp BJ, Caudill MA, Canfield RL. Prenatal choline supplementation improves child sustainí attention: A 7-year follow-up of a randomizí controllí feíing trial. FASEB J. 2022;36:e22054. https://doi.org/10.1096/fj.202101217R
- Institute of Míicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. National Academies Press; 1998.
- Meck WH, Williams CL. Metabolic imprinting of choline by its availability during gestation: implications for memory and attentional processing across the lifespan. Neurosci Biobehav Rev. 2003;27(4):385–399.
- Napoli I, Blusztajn JK, Mellott TJ. Prenatal choline supplementation increases the expression of IGF2 and enhances acetylcholine release in hippocampus and frontal cortex. Brain Res. 2008;1237:124–135.
- Sarter M, Givens B, Bruno JP. The cognitive neuroscience of sustainí attention: where top-down meets bottom-up. Brain Res Rev. 2001;35:146–160.
Frequently Asked Questions about Hydration and Attention
1. How does dehydration affect attention?
Dehydration, even at mild levels, can negatively affect sustained attention. Recent studies have shown that people with elevated serum osmolality (an indicator of dehydration) perform worse on tasks that require maintaining attention for prolonged periods.
2. Which type of attention is most sensitive to hydration status?
Sustained attention is the most affected by dehydration. This function allows you to keep your focus continuously on a task over a long period of time, as in therapy sessions, reading clinical reports, or prolonged driving. Other functions such as working memory or selective attention appear to be less sensitive to mild changes in hydration.
3. How much water should I drink to maintain good attention?
There isn’t a single amount for everyone, but in general an intake of between 1.5 and 2 liters of water per day is recommended. Maintaining adequate hydration helps preserve cognitive performance, especially in tasks that require high levels of attention. It’s important to drink fluids throughout the day, even if you don’t feel thirsty.
4. Is attention in older adults affected by poor hydration?
Yes. Older adults are particularly vulnerable, as their sense of thirst diminishes with age. This can lead to chronic dehydration that negatively impacts attention, increasing the risk of errors, falls, and a reduced ability to follow treatments or participate in cognitive rehabilitation programs.
5. Does drinking water improve attention immediately?
In some cases, yes. In people who are slightly dehydrated, drinking water can quickly improve attention, especially on repetitive or lengthy tasks. However, the most effective approach is to prevent dehydration by maintaining a regular water intake throughout the day.
6. How can I tell if my attention is affected by dehydration?
Some indirect signs include difficulty concentrating, increased errors, mental fatigue, and a feeling of confusion. If these symptoms appear along with dry mouth, headache, or infrequent urination, your attention may be compromised by insufficient hydration.
7. What recommendations are there to improve attention through hydration?
- Drink water regularly, not only when you feel thirsty.
- Include liquids with every meal.
- Monitor fluid intake in hot conditions or during infections.
- Ensure good hydration before activities that require high attention, such as clinical sessions, driving, or exams.
If you likí this article about the impact of hydration and attention on our brain, you will surely be interestí in these articles from NeuronUP:
“This article has been translated. Link to the original article in Spanish:”
Hidratación y atención: el impacto clínico de una relación subestimada
Leave a Reply