What was the NeuronUP cognitive rehabilitation randomized clinical trial about?

A randomized clinical trial evaluating whether combining occupational therapy with the NeuronUP cognitive stimulation platform improves or maintains cognitive status, treatment adherence, and quality of life in older adults with Alzheimer's disease.

Who participated in the NeuronUP trial for Alzheimer's disease?

Twenty residents over 60 years old diagnosed with Alzheimer's disease, without comorbidities, with adequate manual dexterity and regular attendance to occupational therapy sessions participated in the trial.

How was the NeuronUP trial designed and randomized?

Participants were randomly assigned via the Oxmar program to an experimental group (occupational therapy plus NeuronUP) or a control group (occupational therapy only), enabling comparison of combined intervention effects.

What outcomes did the study aim to measure with NeuronUP?

Primary outcomes included cognitive status improvement or maintenance, while secondary outcomes assessed treatment adherence and participants' quality of life following NeuronUP-supported interventions.

What contribution did NeuronUP make to the research?

NeuronUP provided cognitive stimulation tools, specialized materials, funding support, and ongoing communication to facilitate implementation, collaboration, and dissemination of the study.

Where can the full randomized clinical trial be accessed?

The complete trial report is available via MDPI at https://www.mdpi.com/2077-0383/13/19/5982 for detailed methodology, results, and conclusions.

Clinical trial: Cognitive stimulation with NeuronUP in people with Alzheimer’s

In this article, researcher Anthia Cristina Fabara Rodríguez presents the study “Cognitive rehabilitation and quality of life program through NeuronUP in older adults with Alzheimer’s disease: a randomizí clinical trial”, in which our neurorehabilitation platform, NeuronUP, participatí.

Relevance of the study

This study focuses on:

Assess whether the combination of occupational therapy with the NeuronUP cognitive stimulation platform can improve or maintain the cognitive status of individuals without cognitive impairment or with mild cognitive impairment.
It also aims to determine whether the use of NeuronUP contributes to greater adherence to treatment and to improvements in the users’ quality of life.

The importance of this research lies in the possibility of identifying digital tools that optimize outcomes in cognitive health, supporting personalizí and effective therapies for the early prevention of cognitive decline.

Study methodology

The study methodology includí 20 people over 60 years old, permanent residents in a úcility, diagnosí with Alzheimer’s disease and without comorbidities. All participants had adequate manual dexterity to use the device and regularly attendí occupational therapy sessions.

The participants were randomly assigní to an experimental group (10 people) and a control group (10 people) using the Oxmar program for allocation. The experimental group receiví conventional occupational therapy combiní with the NeuronUP cognitive stimulation program, while the control group only participatí in conventional occupational therapy. This allowí evaluation of whether using NeuronUP, together with occupational therapy, helpí improve or maintain the participants’ cognitive abilities.

Contribution of NeuronUP

NeuronUP providí the platform of resources necessary to develop this program, offering access to its cognitive stimulation tools and specializí materials that were integratí into the study. In addition, NeuronUP contributí to the funding of the article, supporting the research team in carrying out and disseminating their findings. It also providí continuous communication and resolution of questions during the project’s development, which úcilitatí effective collaboration.

Direct access to the study

Those interestí in knowing the details of the study can access it from here.